Table 2 Controlled ovarian stimulation outcomes
PPOS Protocol n = 203 n (%) or med (25th -75th ) | Antagonist Protocol n = 406 n (%) med (25th -75th ) | P | P*/** | |
|---|---|---|---|---|
Total dose of gonadotropin (UI) | 2700 (2100–3850) | 2763 (2025–4050) | ||
≤ 2275 | 68 (33.5%) | 136 (33.5%) | 0.38 | 0.78* |
2275–3000 | 72(35.5%) | 131(32.3%) | ||
> 3000 | 63(31%) | (34.2%) | ||
Duration of stimulation (days) | 10.0 (8.0–11.0) | 10.5 (10.0–12.0) | ||
≤ 8 | 52 (25.6) | 46 (11.3) | < 0.001 | 0.34* |
9 | 27 (13.3) | 50 (12.3) | ||
10 | 55 (27.0) | 107 (26.3) | ||
11 | 29 (14.3) | 93 (22.9) | ||
> 11 | 40 (19.7) | 110 (27.0) | ||
Number of follicles with a diameter ≥ 16 mm on the trigger day | 7.0 (4.0–10.0) | 7.0 (5.0–10.0) | ||
≤ 5 | 73 (36.1%) | 129 (32.3%) | 0.21 | 0.29* |
6–9 | 71 (35.1%) | 171 (42.9%) | ||
> 9 | 58 (28.7%) | 99 (24.8%) | ||
Number of monitoring sessions during stimulation | 3 (2–3) | 5 (4–5) | ||
≤ 3 | 159 (78.3%) | 82 (20.6%) | < 0.001 | < 0.001* |
4 | 43 (21.2%) | 260 (65.3%) | ||
> 5 | 1 (0.5%) | 56 (14.0%) | ||
Number of cumulus-oocyte complexes retrieved | 9.0 (7.0–13.0) | 10.0 (7.0–14.0) | ||
≤ 8 | 81 (39.9%) | 150(36.9%) | 0.22 | 0.91** |
9–12 | 65 (32.0%) | 115(28.3%) | ||
> 12 | 57 (28.0%) | 141(34.7%) | ||
Number of MII Oocytes retrieved | 8.0 (6.0–12.0) | 8.0 (5.0–12.0) | ||
≤ 7 | 81(39.9%) | 159 (39.2%) | 0.90 | 0.94** |
9–10 | 57(28.0%) | 110 (27.1%) | ||
> 10 | 65(32.0%) | 137 (33.7%) | ||
Oocyte maturation rate (%) | 88.9 (76.9–100.0) | 88.9 (72.7–100) | ||
≤ 75 | 47 (23.2%) | 124 (30.6%) | 0.05 | 0.38** |
> 75 | 156 (76.8%) | 281 (69.4%) | ||
OSI | 3.6 (1.7–5.8) | 3.6 (1.7–6.7) | ||
≤ 2.24 | 69 (34.0%) | 134 (33.0%) | 0.02 | 0.16** |
2.25–5.24 | 78 (38.4%) | 126 (31.0%) | ||
> 5.24 | 56 (27.6%) | 146 (35.9%) |