Table 2 Relative binding affinity of selected AhR ligands
From: The aryl hydrocarbon receptor: a new frontier in male reproductive system
Ligand | Role | Affinity | Reference |
|---|---|---|---|
TCDD | Agonist | High | |
Benzo[a]pyrene | Agonist | Low | [195] |
FICZ | Agonist | High | [195] |
DEHP (Phthalate) | Agonist/Modulator | Low | [35] |
Resveratrol | Antagonist | Low | |
Curcumin | Mixed (Agonist/Antagonist) | Low | |
Lycopene | Antagonist/Modulator | Low | |
Galangin | Partial Agonist/Antagonist | Low | |
α-Naphthoflavone | Antagonist/Partial Agonist | Low |