Table 1 Clinical features in Men Harboring ARMC2 Variants
Subject | P1 | P2 | Reference Limits |
|---|---|---|---|
Semen Parameter | |||
 Semen volume (ml) | 1.5 | 3.2 |  > 1.5 |
 Semen pH | 7.5 | 7.5 |  |
 Semen concentration (10^6/mL) | 19.2 | 44.5 |  > 15.0 |
 Motility (%) | 41.5 | 0 |  > 40.0 |
 Progressive motility (%) | 23.2 | 0 |  > 32.0 |
Sperm Morphology | |||
 Normal tail (%) | 6.4 (13/202) | 5.9 (12/202) |  > 23.0 |
 Absent flagella (%) | 23.3 (47/202) | 37.1 (75/202) |  < 5.0 |
 Short flagella (%) | 27.7 (56/202) | 42.1 (85/202) |  < 1.0 |
 Coiled flagella (%) | 42.6 (86/202) | 14.9 (30/202) |  < 17.0 |
 DNA Fragmentation Index (DFI)% | 13.4 | 29.9 |  < 15 |
Phenotypic features | |||
 Airway Disease |  |  |  |
 Recurrent airway infections | NO | Yes |  |
 Bronchiectasis | NO | Yes |  |
 Rhinosinusitis | NO | Yes |  |
 Otitis media | NO | Yes |  |
 Situs inversus | NO | NO |  |
 Infertility | Yes | Yes |  |