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Table 3 Allele frequency analysis of rs2293275 in ovarian aging patients and the corresponding subgrous of the Han Chinese population based on different genetic regions

From: Association of LHCGR rs2293275 genotype with ovarian aging in Chinese women: a multicenter population-based study

Genetic region

DOR

POI

OA(%)

PGG.HAN(%)

PDORvs.HAN

OR (95%CI)

PPOIvs.HAN

OR (95%CI)

POAvs.HAN

OR (95%CI)

Southeast

G

361

285

646

(89.47)

49,496

(92.98)

0.002*

1.651

(1.209–2.254)

0.055

1.440

(0.993 ~ 2.090)

0.000**

1.558

(1.225 ~ 1.980)

A

45

31

76

(10.53)

3738

(7.02)

Central

G

182

127

309

(88.29)

36,713

(91.56)

0.458

1.192

(0.750 ~ 1.894)

0.013*

1.793

(1.129 ~ 2.850)

0.029*

1.439

(1.037 ~ 1.997)

A

20

21

41

(11.71)

3385

(8.44)

Southwest

G

414

323

737

(89.23)

7942

(93.02)

0.015*

1.481

(1.080 ~ 2.030)

0.001*

1.774

(1.277 ~ 2.465)

0.000**

1.609

(1.272 ~ 2.036)

A

46

43

89

(10.77)

596

(6.98)

Northwest

G

79

97

176

(88)

10,601

(91.72)

0.046*

1.823

(1.010 ~ 3.290)

0.476

1.256

(0.671 ~ 2.352)

0.061

1.511

(0.981 ~ 2.326)

A

13

11

24

(12)

957

(8.28)

Southcoast

G

229

98

327

(89.84)

23,301

(92.83)

0.234

1.299

(0.844 ~ 2.000)

0.032*

1.848

(1.054 ~ 3.242)

0.030*

1.464

(1.039 ~ 2.064)

A

23

14

37

(10.16)

1801

(7.17)

  1. * p < 0.05 ** p < 0.01