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Table 2 GH supplementation, gonadotropin dosage and the change in hormone levels

From: Exploring the potential benefits of growth hormone co-treatment on embryo quality in IVF: a randomized controlled open-label trial

Characteristic

GH group (n = 51)

Control group (n = 53)

P value

Total dose of rhGH (IU)

120.7 ± 28.90

  

Median duration of GH supplementation (Day)

52.4 ± 19.04

  

FSH (mIU/ml)

   

 on the initiation day of Gn

6.035 ± 1.5517

6.638 ± 1.7685

0.053

 the change from baseline

-0.306 ± 1.5138

0.324 ± 1.6585

0.0458

LH (mIU/ml)

   

 on the initiation day of Gn

3.926 ± 1.7738

4.704 ± 1.5462

0.0017

 the change from baseline

-0.094 ± 3.4831

1.127 ± 1.5142

0.0134

E2 (pg/ml)

   

 on HCG day

2844.112 ± 1244.9055

2735.585 ± 1071.3677

0.6773

 the change from baseline

2812.400 ± 1245.3048

2700.510 ± 1071.4906

0.6631

Progesterone (pg/ml)

   

 on HCG day

0.9386 ± 0.5157

1.2362 ± 0.6094

0.0098

 the change from baseline

0.5595 ± 0.8020

0.9054 ± 0.6505

0.0219

IGF-1 (ng/ml)

   

 on the day of oocyte retrieval

208.998 ± 60.7129

185.958 ± 73.7515

0.027

 the change from baseline

19.895 ± 54.3752

-16.033 ± 68.0917

0.0006

Total Gn dosage (IU)

2213.24 ± 667.015

2573.32 ± 630.009

0.0058

Duration of Gn (Day)

10.1 ± 1.60

10.6 ± 1.30

0.0488

  1. rhGH recombinant human GH, Gn gonadotropin, FSH follicle stimulating hormone, E2 estradiol, LH luteinizing hormone, IGF-1 insulin-like growth factor-1, COS Controlled Ovarian Stimulation