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Table 2 Parameters of laboratory and transfer cycles between the PGT-A and non-PGT-A groups

From: Preimplantation genetic testing for aneuploidy on previously cryopreserved unbiopsied blastocysts: a cohort study in women with IVF pregnancy loss

 

PGT-A

Non PGT-A

P- value

No. of Patients

72

74

 

Women with surviving blastocysts for testing or transfer after warming

70

74

 

Tested blastocysts/total number of surviving blastocysts

257/274 (93.8)

 

Ploidy status of embryos tested

   

 Euploid (%)

125/257 (48.6)

 

 Aneuploid (%)

117/257 (45.5)

 

 Mosaic (%)

15/257 (5.8)

 

Women with at least one euploid embryo

58

 

Cycles of FET

71

90

 

Female age at transfer (y, mean ± SD)

34.5 ± 4.4

33.8 ± 3.3

0.21

Endometrial thickness (mm, median, IQR)

9.2 (8.5–10.4)

9.2 (8.5–10.6)

0.65

Endometrial preparation, n (%)

  

0.52

 Natural cycle

27 (38.0)

37 (41.1)

 

 HRT

27 (38.0)

38 (42.2)

 

 GnRH-a + HRT

17 (23.9)

15 (16.7)

 

No. of blastocyst transferred

1.0 ± 0.1

1.2 ± 0.4

 < 0.01

 1, n (%)

70 (98.6)

74 (82.2)

 < 0.01

 2, n (%)

1 (1.4)

16 (17.8)

 

Cycles with good-quality blastocysts transferred* (%)

38/71 (46.9)

42/90 (46.7)

0.97

Cycles with D5 blastocysts transferred (%)

61/71 (85.9)

76/90 (84.4)

0.76

  1. Data are mean ± SD or median (IQR) or n (%)
  2. PGT-A Preimplantation genetic testing for aneuploidy, FET Frozen embryo transfer, NC Natural cycle, HRT Hormone replacement treatment
  3. *Blastocysts with Gardner’s A or B grades for ICM and TM