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Table 4 Results of univariate and multivariate factors in relation to the live birth rate

From: Potential ability of circulating INSL3 level for the prediction of ovarian reserve and IVF success as a novel theca cell–specific biomarker in women with unexplained infertility and diminished ovarian reserve

Variables

Univariable

Multivariable

OR (95% CI)

p value

OR (95% CI)

p value

Female Age

0.92 (0.829, 1.035)

0.18

  

Duration of infertility

0.79 (0.638, 0.985)

0.03*

  

Type of infertility (DOR vs. UI)

0,285 (0.089, 0.918)

0.03*

  

Previous IVF attempts

Basal FSH level

Serum AMH level

AFC

0.938 (0.514, 1.713)

0.803 (0.677, 0.953)

1.446 (1.035, 2.021)

1.137 (1.013, 1.277)

0.83

0.01*

0.03*

0.03*

0.803 (0.677, 0.953)

0.012*

Total dosage of gonadotropins

Duration of stimulations

1 (0.999, 1,001)

0.764 (0.540, 1.080)

0.846

0.128

  

Estradiol levels on hCG day

1 (1, 1.001)

0.212

  

Number of oocytes retrieved

Number of mature follicles retrieved

Number of PN

Endometrial thickness at day of transfer

Serum INSL3 level

INSL3 level in follicular fluid

1.114 (1.005, 1.234)

1.120 (1.005, 1.248)

1.169 (1.022, 1.336)

1 (0.968, 1.033)

1.001 (0.999, 1.003)

1.000 (0.997, 1.002)

0.03*

0.125

0.02*

1

0.365

0.694

  
  1. *p < 0.05, significant difference
  2. OR: Odds ratio
  3. PN: Pronucleus
  4. hCG: Human chorionic gonadotropin
  5. AFC: Antral follicle count
  6. DOR: Diminished ovarian reserve
  7. BMI: Body Mass Index
  8. IVF: In vitro fertilizasyon
  9. FSH: Follicle stimulating hormone
  10. E2: Estradiol
  11. AMH: Antimullerian hormone
  12. UI: Unexplained infertility