Characteristics | Unexplained (n = 24) | DOR (n = 25) | Control (n = 26) | P value |
---|---|---|---|---|
Female age (years) | 28.41 ± 3.5 | 32.40 ± 4.21a | 29.65 ± 3.91 | 0.001* |
Male age (years) | 35.50 ± 3.70 | 36.12 ± 4.10 | 34.76 ± 3.55 | 0.191 |
Female BMI (kg/m2) | 23.36 ± 3.01 | 24.39 ± 2.60 | 22.10 ± 2.98 | 0.049* |
Duration of infertility (years) | 3.45 ± 1.41 | 5.70 ± 2.81 | 4.21 ± 2.05 | 0.006* |
Infertility type Primary Secondary | 21 3 | 23 2 | 24 2 | 0.78 |
Previous IVF attempts | 1.16 ± 0.38 | 1.80 ± 0.89 | 1.64 ± 0.75 | < 0.001* |
Smoking female | 5/24 | 3/25 | 6/26 | 0.57 |
Smoking male Basal FSH level (IU/L) Basal E2 level (pg/mL) Serum AMH level (ng/mL) AFC Serum INSL3 level (pg/mL) INSL3 level in follicular fluid (pg/mL) | 10/24 6.49 ± 1.25 34.85 ± 13.68 3.01 ± 0.90 10.70 ± 2.80 1775.52 ± 238.18 1193.91 ± 148.55 | 7/25 11.46 ± 3.80 50.12 ± 10.34 0.59 ± 0.25 3.64 ± 1.68 1512.98 ± 184.9 958.67 ± 175.23 | 12/26 7.14 ± 2.10 29.13 ± 10.86 3.29 ± 0.93 11.19 ± 2.60 1742.54 ± 215.14 1043.53 ± 257.31 | 0.38 < 0.001* < 0.001* < 0.001* 0.002* 0.001* < 0.001* |