Fig. 4

G-CSF study design (A). Oocyte retrieval, fertilization and embryonic development (B), and oocyte developmental competence (C) were compared between G-CSF and control groups. Significantly more fertilized oocytes and day-2 embryos, a higher rate of blastocyst acquisition, and higher embryo quality were obtained in the G-CSF group. Implantation rate per transferred embryo was defined as (number of gestational sacs / number of transferred embryos) × 100%. Serum AMH significantly increased after G-CSF priming, while in controls AMH decreased, resulting in higher final concentrations of AMH in the G-CSF group (D). G-CSF, granulocyte colony-stimulating factor; AMH, anti-Müllerian hormone; BBT, basal body temperature; ART, Assisted reproductive technology. Revised from Jinno et al., 2023 [8]