Table 1 Genes with a significant presence of SNVs in patients with ovarian failure
Gene symbol | Position in genome | Nº SNV | Adjusted p-value |
|---|---|---|---|
CDC27 | 17:47117703–47,189,422 | 9 | 5.35E-55 |
ANKRD20A1 | 9:67832765–67,920,552 | 2 | 5.35E-55 |
IGSF3 | 1:116574399–116,667,755 | 1 | 3.64E-54 |
KMT5A | 12:123384132–123,409,353 | 1 | 5.36E-53 |
FAM104B | X:55,143,102–55,161,310 | 2 | 1.08E-38 |
KMT2C | 7:152134922–152,436,644 | 4 | 5.09E-33 |
MTCH2 | 11:47617315–47,642,607 | 5 | 1.48E-25 |
CTBP2 | 10:124984317–125,161,170 | 20 | 1.12E-24 |
AK2 | 1:33007940–33,080,996 | 2 | 1.54E-19 |
ANKRD36B | 2:97492663–97,589,877 | 1 | 7.02E-17 |
WDR89 | 14:63597039–63,641,871 | 4 | 1.60E-11 |
ESRRA | 11:64305497–64,316,743 | 2 | 2.43E-08 |
MST1 | 3:49683947–49,689,501 | 2 | 1.68E-07 |
ZNF717 | 3:75678660–75,785,583 | 9 | 3.59E-07 |
TEKT4 | 2:94871430–94,876,823 | 1 | 4.18E-03 |
CFTR | 7:117287120–117,715,971 | 4 | 5.75E-03 |
HLA-DRB1 | 6:32578769–32,589,848 | 1 | 1.30E-02 |
MLH1 | 3:36993350–37,050,846 | 2 | 2.51E-02 |