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Table 2 Clinical treatment characteristics according to serum uric acid quartiles

From: Effect of serum uric acid level on reproductive outcome in women without polycystic ovary syndrome undergoing in vitro fertilization

 

Quartile 1 (n = 3240)

Quartile 2 (n = 3329)

Quartile 3 (n = 3422)

Quartile 4 (n = 3334)

Ptrend

Ovarian stimulation protocol, n (%)

    

0.523

 GnRH agonist

3124 (96.4)

3204 (96.3)

3311 (96.8)

3219 (96.6)

 

 GnRH antagonist

116 (3.6)

125 (3.8)

111 (3.2)

115 (3.5)

 

Stimulation duration (days)

11 (10–12)

11 (10–12)

11 (10–12)

11 (10–12)

0.439

Total gonadotropin dose (IU)

2025.0 (1500.0-2700.0)

2025.0 (1550.0-2668.8)

2025.0 (1550.0-2662.5)

2100.0 (1650.0-2700.0)

< 0.001

E2 level on trigger day (pg/mL)

1966.5 (1394.1-2701.5)

1946.0 (1384.0-2701.0)

1909.0 (1331.0-2613.0)

1711.4 (1186.0-2411.8)

< 0.001

LH level on trigger day (mIU/mL)

1.1 (0.7–1.6)

1.0 (0.8–1.6)

1.0 (0.7–1.6)

0.9 (0.6–1.4)

< 0.001

P level on trigger day (ng/mL)

0.6 (0.4–0.9)

0.7 (0.5–0.9)

0.6 (0.4–0.9)

0.6 (0.4–0.9)

0.024

Endometrial thickness on trigger day (mm)

10.9 (9.3–12.7)

10.9 (9.4–12.6)

10.9 (9.3–12.6)

10.8 (9.2–12.6)

0.054

No. of oocyte retrieved

11 (8–14)

11 (8–15)

11 (8–15)

11 (8–14)

0.130

Fertilization type, n (%)

    

0.043

 IVF

2502 (77.2)

2616 (78.6)

2753 (80.5)

2667 (80.0)

 

 ICSI

530 (16.4)

516 (15.5)

486 (14.2)

484 (14.5)

 

 IVF + ICSI

208 (6.4)

197 (5.9)

183 (5.4)

183 (5.5)

 

No. of embryos transferred, n (%)

    

0.001

 Single

866 (26.7)

838 (25.2)

845 (24.7)

773 (23.2)

 

 Double

2374 (73.3)

2491 (74.8)

2577 (75.3)

2561 (76.8)

 

Embryo stage at transfer, n (%)

    

0.390

 Cleavage

2799 (86.4)

2882 (86.6)

2958 (86.4)

2907 (87.2)

 

 Blastocyst

441 (13.6)

447 (13.4)

464 (13.6)

427 (12.8)

 

Transfer at least 1 good-quality embryo, n (%)

2579 (79.6)

2667 (80.1)

2736 (80.0)

2564 (76.9)

0.009

  1. Notes: Numeric variables are reported as median (interquartile range) and categorical variables are reported as number (percentage)
  2. Abbreviations: GnRH, gonadotropin-releasing hormone; E2, estradiol; LH, luteinizing hormone; P, progesterone; IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection