Fig. 1
From: MicroRNAs, endometrial receptivity and molecular pathways
Schematic illustration of miRNAs functions in improving the endometrial receptivity. MiRNA works as a regulator of gene expression and is actively involved in regulating embryo development, endometrial functions, and embryo-maternal communications. The verification of functional extracellular miRNAs brings new opportunities for improving implantation outcomes mainly from two aspects: first, intercellular communication through extracellular miRNAs provides a new dimension for understanding the mechanism of implantation; second, extracellular miRNAs have the potential for being effective biomarkers in IVF-ET for detection and prognosis of embryo quality and endometrium receptivity