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Table 4 Comprehensive analysis of misdiagnosed cesarean scar pregnancy patients

From: Systematic evaluation of the efficacy of treatments for cesarean scar pregnancy

Factor

Correct diagnosis group

Misdiagnosis group

p value

Number of patients

780

126

 

Type

  

< 0.001

 Type Ia

142 (18.2%)

6 (4.8%)

 

 Type IIa

462 (59.2%)

32 (25.4%)

 

Number of artificial abortions, median (IQR)

2.0 (1.0, 3.0)

2.0 (1.0, 3.0)

0.054

Number of cesarean sections, median (IQR)

1.0 (1.0, 2.0)

1.0 (1.0, 2.0)

0.51

Interval from last CS (years), median (IQR)

5.0 (3.0, 8.0)

5.0 (3.0, 8.0)

0.95

Gestational age (days), median (IQR)

49.0 (43.0, 58.0)

58.5 (49.0, 74.5)

< 0.001

Diameter of GS (cm), median (IQR)

2.9 (2.0, 4.1)

4.3 (3.2, 5.6)

< 0.001

GS width (cm), median (IQR)

1.5 (1.0, 2.4)

3.3 (2.1, 4.7)

< 0.001

GS area (cm2), median (IQR)

4.5 (2.2, 9.4)

14.9 (6.8, 25.2)

< 0.001

Remnant myometrial thickness (cm), median (IQR)

0.3 (0.2, 0.4)

0.1 (0.0, 0.2)

< 0.001

Color Doppler signal

502 (64.4%)

101 (80.2%)

< 0.001

Fetal heartbeat

358 (45.9%)

16 (12.7%)

< 0.001

Vaginal bleeding

522 (66.9%)

113 (89.7%)

< 0.001

Abdominal pain

221 (28.3%)

33 (26.2%)

0.62

Preoperative hemoglobin, median (IQR)

124.0 (116.0, 131.0)

110.0 (93.0, 119.0)

< 0.001

Preoperative HCG (mIU/ml), median (IQR)

35236.5 (11620.0, 71043.5)

2702.0 (407.4, 18631.0)

< 0.001

Treatments methods

  

< 0.001

 D&E with ultrasonographic guidance

239 (38.3%)

12 (11.3%)

 

 Hysteroscopy

187 (30.0%)

11 (10.4%)

 

 D&E with laparoscopic guidance

37 (5.9%)

8 (7.5%)

 

 Laparoscopy

63 (10.1%)

28 (26.4%)

 

 Laparotomy

98 (15.7%)

47 (44.3%)

 

Liver damage

18 (2.3%)

5 (4.0%)

0.27

Residual tissue

30 (3.8%)

14 (11.1%)

< 0.001

Reoperation

27 (3.5%)

38 (30.2%)

< 0.001

Intraoperative blood loss (ml), median (IQR)

50.0 (30.0, 100.0)

100.0 (50.0, 200.0)

< 0.001

First hemoglobin after operation, median (IQR)

109.0 (98.0, 117.0)

96.0 (86.0, 106.0)

< 0.001

First HCG level after operation, median (IQR)

3097.0 (1018.0, 6978.0)

414.4 (39.0, 2000.2)

< 0.001

Hemoglobin decline, median (IQR)

-11.4 (-17.8, -6.3)

-12.0 (-18.6, -5.7)

0.63

hCG decline, median (IQR)

-90.7 (-93.9, -84.8)

-91.7 (-94.5, -80.1)

0.73

Total hospital stay (d), median (IQR)

8.0 (7.0, 11.0)

10.0 (8.0, 12.5)

< 0.001

Hospital stay after operation (d), median (IQR)

5.0 (4.0, 7.0)

7.0 (6.0, 8.0)

< 0.001

Pain

5 (0.6%)

2 (1.6%)

0.26

Transfusion

46 (5.9%)

30 (23.8%)

< 0.001

  1. Group 1, D&E under ultrasound; Group 2, D&E under hysteroscopy; Group 3, D&E under laparoscopy; Group 4, laparoscopy; Group 5, laparotomy; IQR, interquartile range; HCG, human chorionic gonadotrophin; CS, cesarean sections