From: Systematic evaluation of the efficacy of treatments for cesarean scar pregnancy
Characteristic | Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | p value |
---|---|---|---|---|---|---|
Number of patients | 251(%) | 198(%) | 45(%) | 91(%) | 145(%) | Â |
Age (y) | Â | Â | Â | Â | Â | 0.004 |
 <35 | 159 (63.3) | 127 (64.1) | 25 (55.6) | 74 (81.3) | 105 (72.4) |  |
 ≥35 | 92 (36.7) | 71 (35.9) | 20 (44.4) | 17 (18.7) | 40 (27.6) |  |
Urban residents | Â | Â | Â | Â | Â | 0.014 |
 No | 68 (27.3) | 51 (25.8) | 8 (17.8) | 37 (40.7) | 32 (22.1) |  |
 Yes | 181 (72.7) | 147 (74.2) | 37 (82.2) | 54 (59.3) | 113 (77.9) |  |
Type |  |  |  |  |  | < 0.001 |
 Type Ia (n = 229) | 90(39.3) | 107(46.7) | 21(9.2) | 5(2.2) | 6(2.6) |  |
 Type IIa (n = 421) | 86(20.4) | 101(24.0) | 24(5.7) | 84(20.0) | 126(29.9) |  |
Number of artificial abortions | Â | Â | Â | Â | Â | 0.43 |
 0 | 53 (21.1) | 28 (14.1) | 9 (20.0) | 22 (24.2) | 29 (20.0) |  |
 1 | 66 (26.3) | 48 (24.2) | 12 (26.7) | 23 (25.3) | 43 (29.7) |  |
 2 | 63 (25.1) | 54 (27.3) | 11 (24.4) | 26 (28.6) | 41 (28.3) |  |
 ≥3 | 69 (27.5) | 68 (34.3) | 13 (28.9) | 20 (22.0) | 31 (21.4) |  |
 Unknown | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.7) |  |
Number of cesarean sections | Â | Â | Â | Â | Â | 0.36 |
 1 | 186 (74.1) | 150 (75.8) | 31 (68.9) | 59 (64.8) | 101 (69.7) |  |
 ≥ 2 | 65 (25.9) | 48 (24.2) | 14 (31.1) | 32 (35.2) | 43 (29.7) |  |
 Unknown | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.7) |  |
Interval from last CS (y) | Â | Â | Â | Â | Â | 0.54 |
 ≤ 1 | 26 (10.4) | 24 (12.1) | 2 (4.4) | 14 (15.4) | 15 (10.3) |  |
 2–4 | 81 (32.3) | 63 (31.8) | 13 (28.9) | 35 (38.5) | 44 (30.3) |  |
 ≥ 5 | 138 (55.0) | 110 (55.6) | 29 (64.4) | 40 (44.0) | 82 (56.6) |  |
 Unknown | 6 (2.4) | 1 (0.5) | 1 (2.2) | 2 (2.2) | 4 (2.8) |  |
Gestational age (d) |  |  |  |  |  | < 0.001 |
 ≤ 42 | 64 (25.5) | 32 (16.2%) | 12 (26.7%) | 12 (13.2%) | 23 (15.9%) |  |
 43–63 | 152 (60.6) | 138 (69.7%) | 24 (53.3%) | 53 (58.2%) | 71 (49.0%) |  |
 > 63 | 30 (12.0%) | 27 (13.6%) | 6 (13.3%) | 25 (27.5%) | 40 (27.6%) |  |
 Unknown | 5 (2.0%) | 1 (0.5%) | 3 (6.7%) | 1 (1.1%) | 11 (7.6%) |  |
Diameter of GS (cm), median (IQR) | 2.7 (1.8, 3.8) | 3.0 (2.0, 4.1) | 3.0 (2.1, 4.0) | 3.8 (2.6, 4.9) | 4.3 (2.9, 5.8) | < 0.001 |
GS width (cm), median (IQR) | 1.4 (0.9, 2.0) | 1.5 (0.9, 2.1) | 1.6 (1.2, 2.4) | 2.6 (1.6, 3.7) | 2.8 (1.7, 4.5) | < 0.001 |
GS area (cm2), median (IQR) | 3.6 (1.8, 7.2) | 4.1 (2.1, 8.1) | 5.0 (3.1, 9.7) | 9.5 (4.2, 17.6) | 11.9 (4.8, 23.8) | < 0.001 |
Remnant myometrial thickness, (cm), median (IQR) | 0.3 (0.3, 0.5) | 0.3 (0.2, 0.5) | 0.3 (0.2, 0.4) | 0.2 (0.1, 0.2) | 0.1 (0.0, 0.2) | < 0.001 |
Color doppler signal | Â | Â | Â | Â | Â | 0.024 |
 No | 44 (17.5) | 50 (25.3) | 11 (24.4) | 13 (14.3) | 24 (16.6) |  |
 Yes | 168 (66.9) | 112 (56.6) | 30 (66.7) | 68 (74.7) | 107 (73.8) |  |
 Unknown | 39 (15.5) | 36 (18.2) | 4 (8.9) | 10 (11.0) | 14 (9.7) |  |
Fetal heartbeat | Â | Â | Â | Â | Â | 0.18 |
 No | 127 (50.6) | 104 (52.5) | 25 (55.6) | 61 (67.0) | 83 (57.2) |  |
 Yes | 113 (45.0%) | 87 (43.9) | 18 (40.0) | 24 (26.4) | 56 (38.6) |  |
 Unknown | 11 (4.4%) | 7 (3.5) | 2 (4.4) | 6 (6.6) | 6 (4.1) |  |
Vaginal bleeding |  |  |  |  |  | < 0.001 |
 No | 87 (34.7) | 71 (35.9) | 9 (20.0) | 20 (22.0) | 26 (17.9) |  |
 Yes | 164 (65.3) | 127 (64.1) | 36 (80.0) | 71 (78.0) | 119 (82.1) |  |
Abdominal pain | Â | Â | Â | Â | Â | 0.23 |
 No | 187 (74.5) | 150 (75.8) | 28 (62.2) | 63 (69.2) | 99 (68.3) |  |
 Yes | 64 (25.5) | 48 (24.2%) | 17 (37.8) | 28 (30.8) | 46 (31.7) |  |
Preoperative hemoglobin, median (IQR) | 126.0 (118.0, 131.0) | 126.0 (117.0, 133.0) | 124.0 (116.0, 129.0) | 116.0 (102.0, 129.0) | 115.5 (99.0, 124.5) | < 0.001 |
Preoperative HCG (mIU/ml), median (IQR) | 29439.0 (9071.5, 56865.0) | 38577.5 (12362.5, 72173.5) | 30215.0 (5913.0, 57022.7) | 24538.0 (3083.7, 60903.0) | 26630.0 (2863.0, 65509.0) | 0.069 |