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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: Nur77 improves ovarian function in reproductive aging mice by activating mitophagy and inhibiting apoptosis

Fig. 6

Nur77 slows down ovarian aging in reproductive aging mice. A The mRNA expression levels of Nur77, p53, p21, p16 and H2AX in each group after overexpression of Nur77. B and C The protein expression levels of Nur77, p53, p21, p16 and H2AX in each group after overexpression of Nur77. D Immunofluorescence staining was used to detect the localization and expression of Nur77, p16, H2AX in the ovarian tissues of the each group after overexpression of Nur77. Scale: 50 μm. Error bars, mean ± SEM. n = 6–8 per group. *P < 0.05, **P < 0.01, ***P < 0.001

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