Fig. 5

Nur77 reduced oxidative stress and apoptosis in the ovaries of reproductively aging mice. A The levels of SOD and MDA in ovarian tissue of each group after Nur77 overexpression. B The mRNA expression levels of Bcl2 and Bax in each group after overexpression of Nur77. C and D The protein expression levels of Bcl2 and Bax in each group after overexpression of Nur77. E and F Representative images of TUNEL staining of ovaries tissues, and statistical analysis in each group after overexpression of Nur77. Scale: 50 μm. Error bars, mean ± SEM. n = 6–8 per group. *P < 0.05, **P < 0.01