Table 2 Characteristics in IVF cycles of two groups before and after propensity score matching
Characteristic | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
Growth hormone (n = 1,326) | Control (n = 1,717) | P value | Growth hormone (n = 694) | Control (n = 694) | P value | |
Protocol | 0.509 | 0.67 | ||||
GnRH agonist | 922 (53.70%) | 728 (54.90%) | 367 (52.9%) | 359 (51.7%) | ||
GnRH antagonist | 795 (46.30%) | 598 (45.10%) | 327 (47.1%) | 335 (48.3%) | ||
Change in protocol after IVF failure | 448 (33.8%) | 547 (31.9%) | 0.26 | 237 (34.1%) | 232 (33.4%) | 0.78 |
Total gonadotropin dosage (IU) | 2541.2 ± 944.1 | 2540.6 ± 1142.0 | 0.63 | 2629.3 ± 968.6 | 2633.6 ± 1075.5 | 0.94 |
Total gonadotropin duration (days) | 10.1 ± 2.5 | 9.4 ± 3.0 | < 0.01 | 10.0 ± 2.6 | 9.8 ± 2.6 | 0.15 |
E2 level on hCG day | 3202.4 ± 2452.7 | 2164.2 ± 2093.7 | < 0.01 | 2763.1 ± 2148.0 | 2675.1 ± 2287.8 | 0.46 |
Endometrial thickness (mm) | 11.2 ± 2.6 | 9.7 ± 3.1 | < 0.01 | 10.9 ± 2.7 | 10.2 ± 3.1 | < 0.01 |
Number of oocytes retrieved | 9.0 ± 5.6 | 5.4 ± 5.1 | < 0.01 | 7.6 ± 5.0 | 6.6 ± 5.2 | < 0.01 |
Fertilization type | < 0.01 | 0.17 | ||||
IVF | 677 (51.9%) | 889 (55.6%) | 367 (54.0%) | 337 (51.0%) | ||
ICSI | 590 (45.3%) | 694 (43.4%) | 297 (43.7%) | 315 (47.7%) | ||
IVF + ICSI | 37 (2.8%) | 15 (0.9%) | 16 (2.4%) | 9 (1.4%) | ||
Number of embryos available | 3.7 ± 3.0 | 2.5 ± 2.5 | < 0.01 | 3.3 ± 2.8 | 2.9 ± 2.8 | < 0.01 |
Number of good-quality embryos | 2.0 ± 2.3 | 1.3 ± 1.8 | < 0.01 | 1.8 ± 2.1 | 1.5 ± 2.0 | < 0.01 |
Number of transfers | 1.2 ± 0.8 | 1.0 ± 0.7 | < 0.01 | 1.2 ± 0.7 | 1.1 ± 0.8 | 0.27 |
Freeze-all cycles | 306 (23.1%) | 391 (22.8%) | 0.84 | 161 (23.2%) | 154 (22.2%) | 0.65 |
Embryo type of first transfer | < 0.01 | 0.67 | ||||
Cleavage embryos | 807 (74.0%) | 1039 (80.3%) | 419 (75.4%) | 416 (76.5%) | ||
Blastocyst embryos | 283 (26.0%) | 255 (19.7%) | 137 (24.6%) | 128 (23.5%) | ||