Fig. 1

HAT1 expression is abnormally downregulated in aged GCs. (A) Immunofluorescence of young (6 week) and old (10 month) ovaries stained with HAT1 (green) and DAPI (blue). Scale bar: 500 μm. The amplified views of the boxed area are shown at the bottom. Scale bar: 100 μm. The experiments were repeated three times independently with similar results. (B)-(C) HAT1 protein expression in ovaries from young (6 week) and old (10 month) mice. The experiments were repeated three times independently with similar results. (D) mRNA levels of HAT1 in ovaries from young (6 week) and old (10 month) mice. The experiments were repeated three times independently with similar results. Data are shown as the mean ± SEM, *P < 0.05, **P < 0.01, Student’s t test