Fig. 4
The role of aging-related decline of autophagy in Inflammaging. The aging process leads to a decrease in autophagy, resulting in the abnormal accumulation of proteins and dysfunctional organelles (especially mitochondria), which is one of the mechanisms that lead to Inflammaging. TNFα: tumor necrosis factor α; IL: interleukin. ↑: increase or induction; ↓: decrease or inhibition