Figure 1
From: The emerging use of aromatase inhibitors for endometriosis treatment
Steroidogenic pathway leading to the production of estradiol. Elevated aromatase (P450 arom) expression by endometriotic implant tissue is proposed to lead to the local production of estradiol and subsequent implant growth. P450scc = side chain cleavage enzyme; P450c17 = 17 α-hydroxylase; 3β-HSD = 3β-hydroxysteroid dehydrogenase type 2; 17β-HSD-1 = 17β-hydroxysteroid dehydrogenase type 1.